If we have WP MultiSite, default ProxyPassMatch (^/(.*\.php[345]?(/.*)?)$) will not pass correct script path (for example: example.com/en/wp-admin/load-styles.php) In logs, error is generated: AH01071: Got error 'Primary script unknown\n' Solution that works, is to add additional ProxyPassMatch directive before default ProxyPassMatch. https://wordpress.org/support/topic/multisite-links-broken#post-6395268