Modified loadUserProfile function i discovered using mailuser interface from horfic after many tests and debugs functions recive a value iguals to userid field not sys_userid.
I keep sysuser_id testing for compatibility issues no have any idea if this used in another place and added aditional userid test. 
Tested all things and used auto-response with roundcube with this modifications all worked fine.
More info see here: http://www.howtoforge.com/forums/showthread.php?t=38437&page=15

Deleted the client id check, now he goes directly to the sysuser_id. Now you don't have to use the client id anymore, only more the sysuser_id. Solves issue when client has more than one sysuser

- Added missing remoting functions

Added SOAP support for mail module. Many thanks to Arkadiusz Roch & Artur Edelman from Tri-Plex technology

- Updated Debian installation instructions.

Added a demo client to test the remoting framework.

Several fixes to avoid strict warnings. Made a variable public in db_mysql.inc.php. Added missing language tokens to en_users.lng

- improved several functions in site module
- added server classes to restart services

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